Cerebral Lateralization of the EEG During Perceptual-Motor Integration in Young Adults With Down Syndrome: A Descriptive Study
Background: This study was aimed at investigating cerebral laterality of perceptual-motor integration in persons with DS. Method: Fourteen persons with DS between the ages of 12-39 drummed with their dominant hand (e.g., right hand) following verbal (i.e., drumming to a voice saying "drum"), rhythm (i.e., drumming to the sound of a drum being hit) and melody (i.e., drumming to the loudest beat) instructions. Electroencephalogram (EEG) data at T3 (left hemisphere) and T4 (right hemisphere) was collected and computed as cerebral specialization coefficients during drumming performance. Results: It seems like that our results were consistent with the model of atypical hemisphere processing of verbal information in the right hemisphere in persons with DS, which is opposite to the typical population (Elliott et al., 1987). In addition, the results showed that melody instructions were right hemisphere specialized and rhythm instruction was left hemisphere specialized in persons with DS. Conclusions: This is the first study to systematically examine verbal, rhythm and melody processing in persons with DS. Rhythm and melody are two main components of music. Therefore, these results are promising for understanding mechanisms underlying cerebral processing as well as music therapy for persons with DS.
Phelps, R.A., Pinter, J.D., Lollar, D.J., Medlen, J.G., & Bethell, C.D. (2012). Health care needs of children with Down syndrome and impact of health system performance on children and their families. Journal of Developmental and Behavioral Pediatrics, 33(3), doi: 10.1097/DBP.0b013e3182452dd8
Elliot, D., Edwards, J. M., Weeks, D. J., Lindley, S, & Carnahan, H. (1987). Cerebral specialization in young adults with Down syndrome. American Journal of Mental Deficiency, 91, 480-485.
Hartley, X.Y. (1982). Receptive language processing of Downâ€™s syndrome children. Journal of Mental Deficiency Research, 26, 263-269.
Pipe, M.D. (1988). Atypical laterality and retardation. Psychological Bulletin, 104, 343-349.
Heath, M., Elliott, D., Weeks, D.J., & Chua, R. (2000). A functional -systems approach to movement pathology in persons with Down's syndrome. In D. Weeks, R. Chua & D. Elliott (Eds.), Perceptual-Motor Behavior in Down Syndrome, (pp. 305-320). Champaign IL: Human Kinetics Publishing.
Maraj, B.K.V., Robertson, S.D., Welsh, T.N., Weeks, D.J., Chua, R., Heath, M., â€¦â€¦, & Elliott, D. (2002). Verbal-motor behaviour in persons with Down syndrome. In M. Cuskelly, A. Jobling, & S. Buckley (Eds.), Down syndrome across the life span (pp. 175-193), London, England: Whurr Publishers Ltd.
Weeks, D. J., Chua, R., Weinberg, H., Elliott, D., & Cheyne, D. (2001). A preliminary study using magnetoencephalography to examine brain function in Down syndrome. Journal of Human Movement Studies, 42, 1-18.
.Groen M.A., Alku, P., & Bishop D.V. (2008). Lateralisation of auditory processing in Down syndrome: a study of T-complex peaks Ta and Tb. Biological Psychology, 79(2), 148-157. doi: 10.1016/j.biopsycho.2008.04.003.
Levitin, D.J., Cole, K., Chiles, M., Lai, Z., Lincoln, A., & Bellugi, U. (2004). Characterizing the musical phenotype in individuals with Williams Syndrome. Child Neuropsychology. 10(4), 223-47.
Ringenbach, S.D.R., Gibbons, Z., Chen, C., & Mulvey, G. (2010). Visual-part and music instructions improve timing consistency in bimanual drumming in adults with Down syndrome. Journal of Sport and Exercise Psychology, 32, S48.
Bolduc C., Daoust, A.M., Limoges, E., Braun, C.M.J., & Godbout, R. (2003). Hemispheric lateralization of the EEG during wakefulness and REM sleep in young healthy adults. Brain and Cognition, 53, 193-196.
Bryden, M. P. (1982). Laterality: Functional asymmetry in the intact brain. Academic Press: New York, NY.
Hopyan, T., Dennis, M., Weksberg, R., & Cytrynabum, C. (2001). Music skills and the expressive interception of music in children with Williams-Beuren syndrome: pitch, rhythm, melodic imagery, phrasing, and musical effect. Child Neuropsychology, 7, 42-53.
Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113.
Serrien, D.J., & Brown, P. (2002). The functional role of interhemispheric synchronization in the control of bimanual timing tasks. Experimental Brain Research, 147, 268-272.
Geschwind, N., & Galaburda, A.M. (1987). Cerebral Lateralization: biological mechanisms, associations and pathology. MIT press: Cambridge, MA.
Previc, F.H. (1991). A general theory concerning the prenatal origins of cerebral lateralization in humans. Psychological Review, 98, 299-334.
Latash M.L. & Anson J.G. (1996). What are normal movements in atypical populations? Behavioral and Brain Sciences, 19, 55-106.
Stratford, B. & Ching, Y. (1989). Responses to music and movement in the development of children with Downâ€™s syndrome. Journal of Mental Deficiency Research, 33(pt 1), 13-24.
Pratt, R.R. (2004). Art, dance, and music therapy. Physical Medicine and Rehabilitation Clinics of North America, 15, 827-841.
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